Endocrine Abstracts

Tall cell papillary thyroid carcinoma is known to be associated with an adverse outcome, namely with the early development of locally recurrent or metastatic disease. Therefore the administration of therapeutic radioactive iodine is considered absolutely necessary in the management of such patients. A meningioma may occur in a patient with another neoplastic disease, having also been described in patients with thyroid carcinoma.The aim was to describe th...

Adrenocortical tumorigenesis has been observed in mice. It is speculated to be gonadotropin dependent. In particular LH receptors appear to be found within such adrenal tumors in high density and elevated LH levels may be related to adrenal tumorigenesis. The aim was to describe the case of a patient who after ovariectomy developed a large malignant adrenal tumor. A patient, female, aged 42 presented with uterine leiomyomas. She was treated by surgical excision of the uterus a...

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...

Introduction: Graves’ disease is a multi-system autoimmune disease characterized by hyperthyroidism, ophthalmopathy and pretibial myxedema. The disease presents with hyperthyroidism or more rarely with ophthalmopathy. It runs a various course and many times during its natural course permanent hypothyroidism may ensue.Aim: The aim was to describe the case of a patient with Graves’ disease presenting with ophthalmopathy and subclinical hypothyroi...

Primary hyperaldosteronism may be due to an adrenal adenoma and is an increasingly recognized cause of secondary arterial hypertension. The disease causes hypokalemia and is usually treated surgically by excision of the adrenal adenoma. However, it appears that it may present with a clinical profile without arterial hypertension. The aim was to describe three cases of primary hyperaldosteronism who presented with hypokalemia and an adrenal adenoma with normal blood pressure. A...

Introduction: Hashimoto’s thyroiditis is known to induce nodularity in the thyroid and in some cases to coexist with papillary thyroid carcinoma. However, the effect of the development of Hashimoto’s thyroiditis on the course of nodular goiter is not known.Aim: The aim was to describe the effect of the development of Hashimoto’s thyroiditis in the course of nodular goiter.Methods: A cohort of 12 patients, female, age...

Complete or partial edentulism is common in middle age, especially in postmenopausal women. Edentulism may be the result of either dental problems or periodontitis or both. Periodontitis is characterized by systemic inflammation and may be accompanied by osteoporosis. Osteoporotic patients on treatment with anticatabolic agents may develop osteonecrosis of the jaw. The aim was to present the management of osteoporosis in an edentulous patient with severe periodontitis who deve...

Periodontitis is a serious medical condition which may lead to edentulousness in middle aged patients. It is a chronic inflammatory systemic disorder which affects the oral cavity, the maxilla and mandible. It may be associated with osteoporosis. It presents unique problems in the management of osteoporosis. The patients are in the imminent danger of losing teeth. Some of the antiosteoporotic agents may induce osteonecrosis, while they may complicate the implantation of dental...

MEN (multiple endocrine neoplasia) I disease represents a compilation of multiple endocrine neoplasms affecting a patient in the course of a life-time. It thus represents a phenotype which has survived over many years. Pituitary neoplasms, lipomas and parathyroid hyperplasia are observed in the disease. The aim was to describe a patient with MEN I disease who presented with lipomas and acromegaly in his early adulthood and developed primary hyperparathyroidism in his senior ye...